The main body of evidence comes from statistical analyses performed in New Zealand. The authors found that taking Calcium supplements not only causes transient high levels of blood Calcium but that this was associated with higher relative risk of myocardial infarction.

These studies were statistical comparisons of pooled data sets. Designing a randomised controlled clinical trial to definitively prove the point have been considered but is difficult to design. This is because the research theory of such a trial would have to state that calcium does harm and this makes any trial difficult to organise on ethical grounds.

Currently therefore, statistical analysis can only point out a possible concern. The conclusion at the moment from these studies is that taking Calcium supplements may do more harm to the heart than the good to the bones. The point has at least to be considered that over the counter Calcium pills might not do just what they say on the packet.

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