Amphetamines.

These medications have been widely used in the past as appetite suppressants. They were the most effective diet pills and the most popular for decades from about the 1930's. When in 1979 it became clear that a number of deaths were associated with their use, amphetamines in diet pills were banned by the FDA.

Fenfluramine (Fen-phen) and then dexfenfluramine (Redux) were popular in the 1990's but these too were withdrawn from the market in 1997 following overwhelming evidence that they cause valvular heart disease in a relatively high percentage of those who had taken them.























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