(Reductil): This once daily appetite suppressant was available in the recent past in the UK for the treatment of obesity. Although it's potential to increase the blood pressure of some patients was well known there are now more serious concerns regarding this drugs potential to cause cardiovascular disease.

The concern is that sibutramine increases the risk of heart attacks and strokes in patients with a known or high risk of cardiovascular disease. For this reason sibutramine has been suspended from use in the UK. On January 21st 2010 the European Medicines Agency recommended suspension of marketing authorizations for sibutramine.

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